Hydrocodone is mostly prescribed in pill form with 325 mg. of acetaminaphen, but there is also a hydro/ibuprofen version. Physician told me that most deaths from abuse come from toxicity of too much acetaminaphen, rather than the opiate itself. I don't know if there are toxicity issues on the ibuprofen end. If not, I wonder why that would not be the preferred method.
Maybe ibuprofen is not as effective in conjunction with the opiate, but Tylenol won't touch my headaches while ibuprofen knocks them out. Or maybe ibuprofen is not as toxic in larger amounts, giving the perception that abusers could use more without the worry of toxicity?